Battlestar Galactica: Betrayal is the second and final set to Battlestar Galactica Collectible Card Game and was released on November 8, 2006. It contained 165 cards with an unknown rarity split. Betrayal was available in 15-card booster packs with an MSRP of $3.49. Throughout the distribution, there are 500 hand-autographed rare "Crewman Cally" cards signed by actress Nicki Clyne.
- Betrayal covers the action on Caprica, including the initial Cylon attack, Helo’s trials thereafter, Starbuck’s quest for the Arrow of Apollo, and their initial meeting with the Caprica Resistance, leading up to Starbuck’s and Helo’s return to the fleet with the Arrow and Sharon.
- Betrayal will introduce a new mission mechanic called Link.
- While the only human-Cylon model included in the premiere set was Number Six, Betrayal will include others, including Aaron Doral and Simon.