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Life sciences in the Re-imagined Series

From Battlestar Wiki, the free, open content Battlestar Galactica encyclopedia and episode guide
Revision as of 16:34, 11 October 2006 by Shane (talk | contribs)
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The medical technologies in the Re-imagined Series aren't particularly advanced to that found currently on the real-world Earth. A few special advancements have appeared in the show, despite the character's relative medical similarities to our own, that change the nature of life science as we know it.

The Cancer Cure of Laura Roslin

This section was originally written from a layman's perspective. As such, the information in this section is speculative and with little professional background. Battlestar Wikipedians with more experience and training in biology, medical science, and genetics are strongly encouraged to correct and expand on this section.

The episode "Epiphanies" showed dying President Laura Roslin receiving the fetal blood from Sharon Valerii's and Helo's unborn child, which dramatically annihilates the breast cancer and its subsequent metastasis (spreading) that almost kills Roslin.

The believability of this event is low given that viewers have seen, from the first moment we meet the character of Laura Roslin, that cancer in the Twelve Colonies is just as dire as it is on the real-world Earth.

Killing cancer cells is not inherently a problem in treatment. But killing cancer growths without damaging healthy tissue is the larger issue. As cancer spreads and grows, it infests itself in healthy tissue where surgery is made impossible (brain cancer is commonly inoperable because of the likelihood of damage to critical areas of the brain). Likewise, chemotherapy is less invasive, but can also leave nasty changes to body chemistry and highly undesireable side effects. Roslin mentions that her mother also had breast cancer that she had treated with diloxin therapy, which appears to be a form of chemotherapy. Roslin declined this treatment in favor of Chamalla extract, a treatment that led to interesting side effects, but ultimately failed in slowing or stopping her cancer (as Dr. Cottle predicted).

The cancer cure seen in "Epiphanies" appeared to accomplish the following abilities:

  • Destroyed all cancerous and pre-cancerous cells in the bloodstream (to prevent relapsing)
  • Destroyed all cancer cells in organ tissue while repairing damage to organs with tumors or other infection
  • Differentiated between the host's healthy cells and the cancerous cells
  • Be effective with a relatively small dose, since fetal blood volume is low and cannot be taken in large amounts
  • Left few or no immediate side-effects

There could be some logic to the use of the Cylon hybrid fetal blood, but this requires some stretching of the imagination and perhaps some genetic work.

  • Earth science has confirmed that stem cells, undifferentiated cells found in fetal tissue that change into any needed organ or body part, can be used to aid in cellular repair.[1]
  • The use of fetal stem cells appears to support early research, but with a new twist. According to new research, fetal stem cells from the placentas of babies (born or not) leak into the body of a mother and appear to act as specialized "protectors" that can repair or lessen the effects of damaged tissues or disease. The presence of these cells can be for years, and is compounded by the number of pregnancies of the mother.
  • Earth science has also confirmed that the human immune system mounts a response to cancer, which can lead to the regression of tumors. People with compromised immunity, such as those infected with HIV, suffer from malignancies that are uncommon in the general population. Some cancer researchers have speculated that improving the immune response could provide a cure for cancer possessing all of the above features.
  • Earth science has found that several viruses are capable of rapidly infecting and killing cancerous cells while lacking the same infectivity of healthy cells. Experiments have been conducted in which mice which were deliberately given massive tumors were rapidly cured by direct infections of the tumors by viral agents that did not harm any healthy tissues. In terms of the show, perhaps the Cylon-hybrid cells are capable of mimicking these abilities.
  • Despite their appearance, humanoid Cylon agents are not human, but created. Perhaps in their creation, Cylons designed the humanoid bodies to fight off or identify genetic malfunctions immediately, or may be created without any of the historic genetic abnormalities found in humans that could trigger cancer or other diseases.

Cylon Genetics

The exact technical nature of the humanoid Cylon models is not explained. Apparently, they are the result of incredibly advanced bio-mechanical engineering.[2]

RDM explained that he was afraid that viewers would react to a longer, more detailed explanation as technobabble, and edited the material out as a result. This doesn’t mean that this material is ‘’incorrect’’; nothing Baltar says in the aired episode would be contradicted by further elaboration, as Baltar’s comments that the blood is an “amalgam”, etc. are so vague that further information wouldn’t contradict it. These scenes will probably become available in the Season 2.5 DVD box set.

However, several shots of Baltar going through notes on the genetic structure of the Hybrid’s DNA, etc. can be seen in promo commercials for this episode. Although no screencaps exist for this, careful analysis has yielded several new insights.

File:Uracil.png
Uracil

Baltar is seen looking at this base of a nucleotide which belongs to the Cylon-Human Hybrid: The nucleobase he examines is recognizable as Uracil (which is actually used in mRNA, not DNA):

This would seem to support the notion that the humanoid Cylons are indeed carbon-based, as opposed to silicon-based. However, just as the human body contains the metal Calcium but is not calcium-based, the Cylons incorporate silicon (as noted in the vague reference to "silica pathways") into their physiology, but appear to be carbon-based.

In fact, since silicon does not share the organic nature that enables carbon to form the building blocks of life (silicon can't make as many molecular bonds as carbon), it would be practically impossible for most of a Cylon's body to be anything but a carbon-based life form. Else, the pregnancy between Helo and Sharon Valerii would be physically impossible, even if "love" was needed to make it happen. Certain kinds of radiation have adverse effects on Cylon technology (as shown on Ragnar Anchorage), but this appears to be based on the tissue-level structure of silica pathways, not their underlying cellular basis.

References

  1. According to the podcast for this episode, this was, in fact, the agent of the cure. However, Ron D. Moore believed the explanation would be too much technobabble for audiences and had the explanation truncated.
  2. A great deal of technical insight into the humanoid Cylons, and more specifically, the Cylon-human hybrid fetus, was going to be revealed in “Epiphanies.” However, according to Ron D. Moore’s podcast for this episode, almost all of these were cut, to the point that in the final edit Baltar is left saying that the “blood” of the hybrid is “special”. Many fans thought this explanation was a little too abrupt.