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Trucco became active in television in the late 1990's with appearances in episodes of popular series including Touched by An Angel, Silk Stalkings, Beverly Hills: 90210, Dr. Quinn: Medicine Woman, Sabrina: The Teenage Witch, and Pensacola: Wings of Gold among others. He continued appearing in shows of similar genres like CSI, Wishmaster 4: The Prophecy Fulfilled, Heartbeart, Strong Medicine, CSI: Miami, and others into the 2000's. His latest TV efforts consist of several episodes as "Cooper Lee" in One Tree Hill, and of course his current role as Samuel Anders on Battlestar Galactica (2003).
He is also the lead guitarist of the band "Simpleworld".
In December of 2007, Trucco was involved in a motor vehicle accident. He broke his neck, but managed a full recovery from an injury that most likely should have resulted in paralysis or death. As his injury occurred during the WGA strike, he was fortunate to be able to recover before production resumed. "I didn't want BSG to have to rewrite Anders as a sniveling, whining ball of despair who's hiding out in the corner."  Trucco now has a distinctive scar on the back of his neck. "I've been told they want to incorporate [it] into BSG--but that's all I'm allowed to say."